Figure for the Salk Institute’s Stites lab on how their model (named MAGPIE) integrating mechanistic modeling, bioinformatic analysis, and experimental approaches can uncover new directions and aid in our understanding of cancer biology. Published in npj Systems Biology and Applications.

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Trogdon, M., Abbott, K., Arang, N. et al. Systems modeling of oncogenic G-protein and GPCR signaling reveals unexpected differences in downstream pathway activation. npj Syst Biol Appl 10, 75 (2024). https://doi.org/10.1038/s41540-024-00400-1