AMY CAO 2019

Tissue Cubes: Iron-Deficiency Anemia

This tissue cube exercise, explaining the different stages of iron-deficiency anemia, was designed for a pathology course in the Biomedical Communications program. The goal of the assignment was to communicate the pathological progression of a disease at the tissue scale.


Educated public


Prof. Shelley Wall




October 2018

Tools Used

Adobe Photoshop

Adobe Illustrator

References: Braunstein, E. (July, 2018). Iron Deficiency Anemia. Retrieved from Coad, J., & Pedley, K. (2014). Iron deficiency and iron deficiency anemia in women. Scandinavian Journal of Clinical and Laboratory Investigation, 74(sup244), 82–89. Dallman, P. R. (1986). Biochemical Basis for the Manifestations of Iron Deficiency. Annual Review of Nutrition, 6(1), 13–40. de Benoist B et al. (2008). Worldwide prevalence of anaemia 1993-2005. WHO Global Database on Anaemia Geneva, World Health Organization.

Johnson-Wimbley, T. D., & Graham, D. Y. (2011). Diagnosis and management of iron deficiency anemia in the 21st century. Therapeutic Advances in Gastroenterology, 4(3), 177–184. Lopez, A., Cacoub, P., Macdougall, I. C., & Peyrin-Biroulet, L. (2016). Iron deficiency anaemia. The Lancet, 387, 907–916. Nemeth E, Tuttle MS, Powelson J, et al. (2004). Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science, 306(5704), 2090-2093.