Tissue Cubes: Iron-Deficiency Anemia

This tissue cube exercise, explaining the different stages of iron-deficiency anemia, was designed for a pathology course in the Biomedical Communications program. The goal of the assignment was to communicate the pathological progression of a disease at the tissue scale.


Educated public


Prof. Shelley Wall




October 2018

Tools Used

Adobe Photoshop

Adobe Illustrator

References: Braunstein, E. (July, 2018). Iron Deficiency Anemia. Retrieved from https://www.merckmanuals.com/en-ca/professional/hematology-and-oncology/anemias-caused-by-deficient-erythropoiesis/iron-deficiency-anemia. Coad, J., & Pedley, K. (2014). Iron deficiency and iron deficiency anemia in women. Scandinavian Journal of Clinical and Laboratory Investigation, 74(sup244), 82–89. http://doi.org/10.3109/00365513.2014.936694. Dallman, P. R. (1986). Biochemical Basis for the Manifestations of Iron Deficiency. Annual Review of Nutrition, 6(1), 13–40. http://doi.org/10.1146/annurev.nu.06.070186.000305. de Benoist B et al. (2008). Worldwide prevalence of anaemia 1993-2005. WHO Global Database on Anaemia Geneva, World Health Organization.

Johnson-Wimbley, T. D., & Graham, D. Y. (2011). Diagnosis and management of iron deficiency anemia in the 21st century. Therapeutic Advances in Gastroenterology, 4(3), 177–184. http://doi.org/10.1177/1756283X11398736. Lopez, A., Cacoub, P., Macdougall, I. C., & Peyrin-Biroulet, L. (2016). Iron deficiency anaemia. The Lancet, 387, 907–916. http://doi.org/10.1016/S0140-6736(15)60865-0. Nemeth E, Tuttle MS, Powelson J, et al. (2004). Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science, 306(5704), 2090-2093.


AMY CAO 2019